Addressing the Impact of Psychiatric Drugs on Metabolic Health and Embracing a Holistic Approach
In the previous blog post, we explored the importance of metabolic health and mitochondrial function in psychiatric disorders and how longevity medicine interventions can help improve mental health outcomes. In this post, we will discuss how psychiatric drugs and interventions can affect metabolic health and the importance of a holistic approach to mental health.
Reducing Metabolic Side Effects in Psychiatry
Certain psychiatric drugs and interventions can negatively affect metabolic health, leading to weight gain, dyslipidemia, and insulin resistance. These side effects can worsen metabolic disorders and increase cardiovascular disease risk. By incorporating metabolic metrics and biomarkers into psychiatric assessments and treatments, we can better monitor and optimize the impact of these interventions on both mental and physical health.
Measuring Metabolic Health
In addition to lab assessments like hsCRP, HgbA1c, lipid panel, homocysteine, and fasting insulin, I use CGMs to monitor patients' metabolic responses to food, exercise, and stress. HgbA1c provides an average blood glucose level over the past two to three months, while the lipid panel measures cholesterol and triglyceride levels, both of which are important indicators of cardiovascular health. Homocysteine is an amino acid linked to heart disease, and fasting insulin measures insulin levels after an overnight fast.
Inflammatory Biomarkers
HsCRP (otherwise known as high-sensitivity C-reactive protein) is a blood test used to measure the level of C-reactive protein, a marker of inflammation in the body. Elevated hsCRP levels are associated with an increased risk of cardiovascular disease, as well as chronic conditions such as diabetes and obesity. Inflammation has also been linked to mental health issues, as it can negatively impact brain function, neurotransmitter production, and synaptic plasticity. Therefore, monitoring hsCRP levels can provide valuable insights into the relationship between inflammation and mental health in patients - and can help us personalize treatment focus on reducing inflammation.